Haploidentical hematopoietic stem cell transplantation as individual treatment option in pediatric patients with very high-risk sarcomas.

Thomas Eichholz,Michaela Döring,Stefano Giardino,Bernd Gruhn,Christian Seitz,Tim Flaadt,Wolfgang Schwinger,Martin Ebinger,Ursula Holzer,Markus Mezger,Heiko-Manuel Teltschik,Monika Sparber-Sauer,Ewa Koscielniak,Michael Abele,Rupert Handgretinger, Peter Lang

Frontiers in oncology（2023）

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摘要

Haplo-HSCT for consolidation after conventional therapy seems to be of interest for some, but not for the majority of patients with high-risk pediatric sarcomas. Evaluation of its future use as basis for subsequent humoral or cellular immunotherapies is necessary.

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关键词

Ewing sarcoma,haploidentical hematopoietic stem cell transplantation,pediatric sarcoma,rhabdomyosarcoma,soft tissue sarcoma

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