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Portable and green solid contact potentiometric sensor for the rapid and direct assay of clozapine in post-mortem rat liver and dosage forms: An analytical approach to forensic and pharmaceutical samples

Microchemical Journal(2023)

Cited 2|Views6
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Abstract
•Misdiagnosis of clozapine intoxication with stroke in emergency rooms.•The first Portable green potentiometric sensor for in-site assay of clozapine in post-mortem rat liver and tablets.•Significance of the assay to medical malpractice defense, plaintiff attorneys, and insurance companies.•Docking study to evaluate Clozapine-ionophore complex stability.•Evaluating the proposed sensor greenness compared to the reported method applying GAPI.
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Key words
Clozapine,Intoxication,Portable sensor,Green chemistry,Ionophore doping
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