U-shaped association between serum IGF2BP3 and T2DM: A cross-sectional study in Chinese population.

Xiaoying Wu, Wei Wang,Shujin Fan,Lili You,Feng Li,Xiaoyun Zhang,Hongshi Wu,Juying Tang,Yiqin Qi,Wanting Feng,Li Yan,Meng Ren

Journal of diabetes（2023）

引用 5|浏览26

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摘要

Seven significantly altered m A RNA methylation genes were identified in T2DM. There was a U-shaped association between serum IGF2BP3 levels and odds of T2DM in the general Chinese adult population. This study provides important evidence for further examination of the role of m A RNA methylation, especially serum IGF2BP3 in T2DM risk assessment.

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关键词

2型糖尿病,N6 -甲基腺苷(m6A),N6-methyladenosine (m6A) RNA methylation,RNA甲基化,gene expression omnibus,insulin-like growth factor 2 mRNA-binding protein (IGF2BP)3,type 2 diabetes mellitus,基因表达数据库,胰岛素样生长因子2 mRNA结合蛋白3 (IGF2BP3)

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