Utility of BAP1, p16 and MTAP immunohistochemistry in cytological and histological samples of pleural mesotheliomas.

Vera Amacher,Peter Karl Bode,Holger Moch,Daniela Lenggenhager,Bart Vrugt

Acta cytologica（2023）

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Abstract

Concordant BAP1, MTAP and p16 expression is found between cytological and corresponding histological samples, indicating that a reliable diagnosis of MPM can be made on cytology only. Of the three markers BAP1 and MTAP are most reliable in distinguishing malignant from reactive mesothelial proliferations.

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