Evaluation of cell collection efficiency in non-mobilized adult donors for autologous chimeric antigen receptor T-cell manufacturing.

Juan A Piñeyroa,Joan Cid,Alexandru Vlagea,Gloria Carbassé, Paola Henao, Noemí Bailo,Valentín Ortiz-Maldonado,Núria Martínez-Cibrian,Marta Español,Julio Delgado,Álvaro Urbano-Ispizua,Miquel Lozano

Vox sanguinis（2023）

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摘要

The knowledge of the MNC and lymphocyte CE1 of each apheresis device used to collect cells for CAR T therapy, together with the goal of the number of cells required, is essential to define the volume to be processed and to ensure the success of the collection.

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关键词

CAR T-cell,apheresis,collection efficiency,mononuclear cell collection

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