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Association of alopecia areata with alcohol use disorder, attention-deficit hyperactivity disorder and insomnia: a case-control analysis using the All of Us research programme

Tejas P. Joshi, Harrison Zhu, Miranda Tomaras, Maci Terrell, Emily Strouphauer, Haleigh Stafford, Fyona Okundia, Alexander Iacobucci, Swathi Holla, Darien Hinson, Hannah Hanania, Clarissa Gonzalez, Francesca Gedeon, Danielle Garcia, Sarah Friske, Briana Fernandez, Andrea Stolar, Vicky Ren

Clinical and experimental dermatology(2023)

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Abstract
Alopecia areata (AA) is a chronic inflammatory disorder typically characterized by non-scaly, discrete patches of non-scarring hair loss. While recent research has shown a clear link between AA and anxiety and depression, the association of AA with other psychiatric co-morbidities has been poorly studied. In this National Institutes of Health database study, we show AA to be significantly associated with alcohol use disorder, attention-deficit/hyperactivity disorder, and insomnia. Dermatologists may be uniquely situated to screen for these previously under-recognized co-morbidities and refer to mental health services when appropriate.
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Key words
alopecia areata,alcohol use disorder,attention–deficit hyperactivity disorder,insomnia,alcohol use
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