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Periostin in ovarian carcinoma: from heterogeneity to prognostic value.

Ludmila Lozneanu,Irina-Draga Caruntu,Cornelia Amalinei,Mihaela Moscalu,Bogdan Gafton,Mihai Vasile Marinca,Andreea Rusu,Raluca Balan,Simona-Eliza Giusca

Folia histochemica et cytobiologica（2023）

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Abstract
The comparative assessment of POSTN immunoexpression in two tumor compartments: in tumor cells and stroma, by use of different scoring systems revealed that higher stromal POSTN levels are evidently correlated with unfavorable clinical features and poorer prognosis, while POSTN expression in tumor cells seems to be associated with a better patient outcome.
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Key words
epithelial tumor cells,ovarian cancer,periostin,stromal cells,survival,therapy response
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