Infiltrating immune cells in prostate cancer tissue after androgen deprivation and radiotherapy.

Ann Erlandsson,Marie Lundholm,Johan Watz,Anders Bergh, Elitsa Petrova,Farhood Alamdari,Thomas Helleday,Sabina Davidsson,Ove Andren,Firas Tarish

International journal of immunopathology and pharmacology（2023）

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摘要

Neoadjuvant ADT in combination with RT results in a higher inflammatory response compared to RT or ADT alone. The mIHC method may be a useful tool for investigating infiltrating immune cells in PCa biopsies to understand how immunotherapeutic approaches can be combined with current PCa therapies.

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关键词

Prostate cancer,androgen deprivation therapy,immune cells,multiplex IHC,radiotherapy

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