Atherosclerotic patients with diabetes mellitus may break through the threshold of healthy TMAO levels formed by long-term statins therapy.

Heliyon(2023)

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Abstract
Diabetics have abnormally high plasma TMAO levels even under continuous statins treatment, which may contribute to the development and progression of atherosclerosis. Therefore, it is necessary to focus on monitoring TMAO levels in diabetic patients to reduce adverse cardiovascular events in diabetic patients.
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Key words
Atherosclerosis,Diabetes,LASSO regression,Risk factors,Trimethylamine N-Oxide
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