Causal relationship between atrial fibrillation and leukocyte telomere length: A two sample, bidirectional Mendelian randomization study.

Zimo Sha,Tianzhichao Hou,Taojie Zhou,Yang Dai,Yangyang Bao,Qi Jin,Jing Ye,Yiming Lu,Liqun Wu

Frontiers in cardiovascular medicine（2023）

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摘要

The presence of AF leads to LTL shortening rather than the other way around. Aggressive intervention for AF may delay the telomere attrition.

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关键词

atrial fibrillation,bidirectional Mendelian randomization (MR),expression quantitative trait loci (eQTL),genome-wide association study,leukocyte telomere length,protein quantitative trait loci (pQTL)

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