No transmitted drug resistance to HIV integrase strand-transfer inhibitors after their scale-up in Estonia in 2017.
Journal of global antimicrobial resistance(2023)
摘要
Although no major INSTI mutations were found, close monitoring of INSTI SDRMs is needed considering the extensive use of the first- and second-generation INSTIs. PR-RT TDR is slowly rising in Estonia, indicating the need for continuous surveillance in the future. Low genetic barrier NNRTIs should be avoided in the treatment regimens.
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关键词
HIV,HIV epidemiology,HIV-transmitted drug resistance,Integrase strand transfer inhibitor,Treatment naïve
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