Annao Pingchong decoction alleviate the neurological impairment by attenuating neuroinflammation and apoptosis in intracerebral hemorrhage rats.

Chun Guo, Xuqing Zhou,Xu Wang, Haojie Wang,Jian Liu, Jinxi Wang,Xiaoyuan Lin,Shihui Lei, Yi Yang,Kai Liu,Hongping Long,Desheng Zhou

Journal of ethnopharmacology（2023）

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摘要

We found that ANPCD had neuroprotective effect in clinical work. Here, we also found that the action mechanism of ANPCD might be related to attenuate neuroinflammation and apoptosis. These effects were achieved by inhibiting the expression of HMGB1, TLR4 and NF-κB p65.

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关键词

Annao Pingchong decoction,Apoptosis,HMGB1,Intracerebral hemorrhage,Neuroinflammation,TLR4

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