Similarity and difference between systemic lupus erythematosus and NZB/W F1 mice by multi-omics analysis.

Kenji Okuma,Takuma Oku,Chiyomi Sasaki,Koji Kitagori,Tsuneyo Mimori,Ichiro Aramori,Yoshitaka Hirayama,Hajime Yoshifuji

Modern rheumatology（2023）

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摘要

NZB/W F1 mice are a generally suitable model of SLE for analyzing the pathophysiology and treatment response of T/B cells and monocytes/macrophages, and their secreted cytokines.

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关键词

NZB/W F1 mouse,cytokine,multi-omics,systemic lupus erythematosus,transcriptome

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