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The Application of HPLC-FLD and NMR in the Monitoring of Therapy Efficacy in Alpha-Mannosidosis.

Maroš Krchňák,Rebeka Kodríková,Mária Matulová,Marek Nemčovič,Iveta Uhliariková,Jaroslav Katrlík,Anna Šalingová,Anna Hlavatá,Katarína Juríčková,Peter Baráth,Ján Mucha,Zuzana Pakanová

Frontiers in bioscience (Landmark edition)（2023）

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Abstract
The application of both HPLC-FLD and NMR in quantification of oligosaccharide biomarkers is a suitable approach for monitoring of therapy efficacy in alpha-mannosidosis patients.
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Key words
HPLC,NMR,alpha-mannosidosis,mass spectrometry,velmanase alpha
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