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Variable Landscape of PD-L1 Expression in Breast Carcinoma as Detected by the DAKO 22C3 Immunohistochemistry Assay.

Natalie Danziger,Ethan S Sokol,Ryon P Graf,Matthew C Hiemenz,Jake Maule,Vamsi Parimi,Carlo Palmieri,Lajos Pusztai,Jeffrey S Ross,Richard S P Huang

The oncologist（2023）

Cited 0|Views15
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Abstract
The subtypes of breast cancer have distinct patterns of PD-L1 expression, supporting that further research of immunotherapies may include specific evaluation of optimum cutoffs for non-TNBC patients. In TNBC, PD-L1 positivity is not associated with other clinicopathologic or genomic features and should be integrated into future studies of immunotherapy efficacy.
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PD-L1,biomarkers,breast cancer,comprehensive genomic profiling,immunotherapy,triple-negative breast cancer
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