Atypical Neurofibromas reveal distinct epigenetic features with proximity to benign peripheral nerve sheath tumor entities.

Neuro-oncology（2023）

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摘要

Our data suggest that ANF with varying histological morphology show distinct epigenetic similarities and cluster in proximity to benign peripheral nerve sheath tumor entities. Future investigations should pay special respect to correlating this methylation pattern to clinical outcome.

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关键词

Atypical neurofibroma,DNA methylation,classification,diagnostic marker,peripheral nerve sheath tumors

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