Synthetic Cooling Agent in Oral Nicotine Pouch Products Marketed as "Flavor-Ban Approved".

Sairam V Jabba,Hanno C Erythropel, Jackson G Woodrow,Paul T Anastas,Stephanie S O'Malley,Suchitra Krishnan-Sarin,Julie B Zimmerman,Sven E Jordt

bioRxiv : the preprint server for biology（2023）

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摘要

Synthetic cooling agents such as WS-3 found in 'Flavor-Ban Approved' Zyn-"Chill" can provide a robust cooling sensation with reduced sensory irritancy, thereby increasing product appeal and use. The label "Flavor-Ban Approved" is misleading and may implicate health benefits. Regulators need to develop effective strategies for the control of odorless sensory additives used by the industry to bypass flavor bans.

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