3D genome-selected microRNAs to improve Alzheimer's disease prediction.

Keyi Li,Runqiu Chi,Liangjie Liu,Mofan Feng,Kai Su,Xia Li,Guang He,Yi Shi

Frontiers in neurology（2023）

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摘要

With the assistance of the 3D genome, we were able to train more accurate models by selecting fewer but more discriminatory miRNAs, as witnessed by several ML models. These interesting findings indicate that the 3D genome has great potential to play an important role in future AD research.

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关键词

3D genome,Alzheimer's disease,biomarkers,machine learning,microRNA

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