Surgical management of chronic rhinosinusitis with nasal polyps under local anaesthesia: indications and results

Objective. Our objective was to specify the indications and duration of effectiveness of Awake Patient Polyp Surgery (APPS) in Chronic Rhinosinusitis with Nasal Polyps (CRSwNP). Secondary objectives were to evaluate complications and Patient-Reported Ex-perience (PREMs) and Outcome Measures (PROMs).Methods. We collected information regarding sex, age, comorbidities and treatments. Dura-tion of effectiveness was the duration of non-recurrence defined by the time between APPS and a new treatment. Nasal Polyp Score (NPS) and Visual Analogic Scales (VAS, from 0/10 to 10/10) for nasal obstruction and olfactory disorders were assessed preoperatively and one month after surgery. PREMs were evaluated using a new tool: the APPS score.Results. Seventy-five patients were enrolled (SR = 3.1, mean age = 60.9 +/- 12.3 years). 60% of patients had a previous history of sinus surgery, 90% had stage 4 NPS and more than 60% had overuse of systemic corticosteroids. Mean time of non-recurrence was 31.3 +/- 2.3 months. We found a significant improvement (all p < 0.001) for NPS (3.8 +/- 0.4 vs 1.5 +/- 0.6), VAS obstruction (9.5 +/- 1.6 vs 0.9 +/- 1.7) and VAS olfactory disorders (4.9 +/- 0.2 vs 3.8 +/- 1.7). Mean APPS score was 46.3 +/- 5.5/50.Conclusions. APPS is a safe and efficient procedure in the management of CRSwNP.