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Randomized Trial of Targeted Transendocardial Mesenchymal Precursor Cell Therapy in Patients With Heart Failure.

Emerson C Perin,Kenneth M Borow,Timothy D Henry,Farrell O Mendelsohn,Leslie W Miller,Elizabeth Swiggum,Eric D Adler, David H Chang,R David Fish,Alain Bouchard, Margaret Jenkins,Alex Yaroshinsky,Jack Hayes, Olga Rutman, Christopher W James,Eric Rose,Silviu Itescu,Barry Greenberg

Journal of the American College of Cardiology（2023）

Cited 9|Views23
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Abstract
The primary and secondary endpoints of the trial were negative. Positive signals in prespecified, and post hoc exploratory analyses suggest MPCs may improve outcomes, especially in patients with inflammation.
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Key words
cell therapy,heart failure with reduced ejection fraction,major adverse cardiovascular events,mesenchymal precursor cells
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