Effect of budesonide on pulmonary activity of multidrug resistance-associated protein 1 assessed with PET imaging in rats

Severin Mairinger,Irene Hernández-Lozano, Lena Zachhuber,Thomas Filip,Mathilde Löbsch,Markus Zeitlinger,Marcus Hacker,Carsten Ehrhardt,Oliver Langer

European Journal of Pharmaceutical Sciences（2023）

引用 0|浏览8

暂无评分

摘要

•Measurement of pulmonary MRP1 activity with PET.•Intratracheal aerosolization of budesonide in rats.•Assessment of the effect of budesonide on pulmonary MRP1 activity.•Use of MK571 as a control inhibitor.•Transporter-mediated DDI at the pulmonary epithelium.

查看译文

关键词

Multidrug resistance-associated protein 1,Pulmonary epithelium,Inhaled budesonide,Positron emission tomography,Drug–drug interaction

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要