Potential involvement of polycystins in the pathogenesis of ameloblastomas: Analysis based on bioinformatics and immunohistochemistry

Archives of Oral Biology(2023)

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摘要
•Polycystin-1 and polycystin-2 had higher expression in ameloblastoma.•PKD1 and PKD2 genes had a high diagnostic utility for ameloblastoma.•Allopurinol interacts with PKD2 gene and could be a potential drug candidate.•Polycystins offer a new perspective on the targeted therapies of ameloblastoma.
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AUC,ADPKD,DEGs,EMT,GEO,GO,KEGG,PBS,PCs,PC-1,PKD1,PC-2,PKD2,PPI,ROC,TIMPs,WHO
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