Urine Protein Immunofixation Electrophoresis: Free Light Chain Urine Immunofixation Electrophoresis Is More Sensitive than Conventional Assays for Detecting Monoclonal Light Chains and Could Serve as a Marker of Minimal Residual Disease.

Gurmukh Singh,Nkechi Arinze,David M Manthei, Frederick V Plapp,Roni J Bollag

Laboratory medicine（2023）

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摘要

The new method of urine immunofixation is significantly more sensitive and more efficient than the conventional method for detecting MLCs in urine. The new assay appears to be sensitive enough to prove that MLCs serve as a marker of MRD in MM.

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关键词

free light chain immunofixation,minimal residual disease,monoclonal gammopathy,multiple myeloma,serum free light chain,urine immunofixation

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