Effect of laser-assisted reconstructive surgical therapy of peri-implantitis on protein biomarkers and bacterial load.

Riccardo Di Gianfilippo,Chin-Wei Wang,Yuying Xie,Janet Kinney,James Sugai,William V Giannobile,Hom-Lay Wang

Clinical oral implants research（2023）

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摘要

Reconstructive therapy of peri-implantitis significantly altered PICF protein biomarker and microbial levels during the healing process. The adjunctive use of Er:YAG laser significantly modulated the inflammatory response through reduced levels of MMP-9 and VEGF during the postsurgical period. The bacterial load was reduced immediately after therapy, but recolonization was observed by 4 weeks in both groups.

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bone implant interactions,bone regeneration, clinical trials,guided tissue regeneration, bone regeneration,lasers,microbiology,periodontology,wound healing

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