Accurate diagnosis of prostate cancer by combining Proclarix with magnetic resonance imaging.

BJU international（2023）

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摘要

When combined with mpMRI and prostate volume, Proclarix reliably predicted csPCa and ruled out men with no or indolent cancer. A large reduction of two thirds of unneeded biopsies was achieved. Proclarix can further be used with high confidence to reliably detect csPCa in men with an indeterminate PI-RADS score 3 mpMRI. Despite these encouraging results, further validation is needed.

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关键词

PSA,Proclarix,Proclarix-MRI score,biomarkers,biopsy,cathepsin D,diagnosis,mpMRI,prostate cancer,thrombospondin-1

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