DNMT1 involved in the analgesic effect of folic acid on gastric hypersensitivity through downregulating ASIC1 in adult offspring rats with prenatal maternal stress.
CNS neuroscience & therapeutics（2023）
Abstract
These results indicate that increased DNMT1 contributes to the analgesic effect of FA on PMS-induced GHS by reducing ASIC1 expression and sensitivity.
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Key words
DNA methyltransferase,acid-sensing ion channel,dorsal root ganglion,folic acid,functional dyspepsia,gastric hypersensitivity
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