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Label-free in vitro assays predict the potency of anti-disialoganglioside chimeric antigen receptor T-cell products.

Meghan Logun,Maxwell B Colonna,Katherine P Mueller,Divya Ventarapragada,Riley Rodier,Chaitanya Tondepu,Nicole J Piscopo,Amritava Das,Stacie Chvatal,Heather B Hayes,Christian M Capitini,Daniel J Brat,Theresa Kotanchek,Arthur S Edison,Krishanu Saha,Lohitash Karumbaiah

Cytotherapy（2023）

引用 0|浏览19
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摘要
These studies establish impedance sensing as a high-throughput, label-free assay for preclinical potency testing of CAR T cells against solid tumors.
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关键词
CAR-T therapy,T-cell potency,cellular Immunotherapy,glioblastoma
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