Aggravation of hyperthyroidism following severe acute respiratory syndrome coronavirus-2 mRNA vaccine booster administration in a patient with Graves' disease.

British Journal of Hospital MedicineVol. 84, No. 2 Case ReportAggravation of hyperthyroidism following severe acute respiratory syndrome coronavirus-2 mRNA vaccine booster administration in a patient with Graves' diseaseKyle Cilia, Arlene Gatt, Naomi Piscopo, Simon Mifsud, Sandro VellaKyle CiliaCorrespondence to: Kyle Cilia; E-mail Address: [email protected]Department of Medicine, Mater Dei Hospital, Msida, MaltaSearch for more papers by this author, Arlene GattDepartment of Diabetes and Endocrinology, Mater Dei Hospital, Msida, MaltaSearch for more papers by this author, Naomi PiscopoDepartment of Medicine, Mater Dei Hospital, Msida, MaltaSearch for more papers by this author, Simon MifsudDepartment of Diabetes and Endocrinology, Mater Dei Hospital, Msida, MaltaSearch for more papers by this author, Sandro VellaDepartment of Diabetes and Endocrinology, Mater Dei Hospital, Msida, MaltaSearch for more papers by this authorKyle Cilia; Arlene Gatt; Naomi Piscopo; Simon Mifsud; Sandro VellaPublished Online:14 Feb 2023https://doi.org/10.12968/hmed.2022.0379AboutSectionsView articleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareShare onFacebookTwitterLinked InEmail View article References Bostan H, Ucan B, Kizilgul M et al.. Relapsed and newly diagnosed Graves' disease due to immunization against COVID-19: a case series and review of the literature. J Autoimmun. 2022;128:102809. https://doi.org/10.1016/j.jaut.2022.102809 Crossref, Medline, Google ScholarBrix TH, Kyvik KO, Hegedüs L. What is the evidence of genetic factors in the etiology of Graves' disease? A brief review. Thyroid. 1998;8(8):727–734. https://doi.org/10.1089/thy.1998.8.727 Crossref, Medline, Google ScholarChee YJ, Liew H, Hoi WH. SARS-CoV-2 mRNA vaccination and Graves' disease: a report of 12 cases and review of the literature. J Clin Endocrinol Metab. 2022;107(6):e2324–e2330. https://doi.org/10.1210/clinem/dgac119 Crossref, Medline, Google ScholarGoblirsch TJ, Paulson AE, Tashko G, Mekonnen AJ. Graves' disease following administration of second dose of SARS-CoV-2 vaccine. BMJ Case Rep. 2021;14(12):e246432. https://doi.org/10.1136/bcr-2021-246432 Crossref, Medline, Google ScholarKanduc D, Shoenfeld Y. Molecular mimicry between SARS-CoV-2 spike glycoprotein and mammalian proteomes: implications for the vaccine. Immunol Res. 2020;68(5):310–313. https://doi.org/10.1007/s12026-020-09152-6 Crossref, Medline, Google ScholarLui DTW, Lee KK, Lee CH et al.. Development of Graves' disease after SARS-CoV-2 mRNA vaccination: a case report and literature review. Front Public Health. 2021;9:778964. https://doi.org/10.3389/fpubh.2021.778964 Crossref, Medline, Google ScholarOğuz SH, Şendur SN, I·remli BG et al.. SARS-CoV-2 vaccine-induced thyroiditis: safety of revaccinations and clinical follow-up. J Clin Endocrinol Metab. 2022;107(5):e1823–e1834. https://doi.org/10.1210/clinem/dgac049 Crossref, Medline, Google ScholarPaluchamy TG. Disease: clinical significance and management. In: Gensure R (ed). Graves' disease. London: IntechOpen; 2021. https://doi.org/10.5772/intechopen.96418 Google ScholarPujol A, Gómez LA, Gallegos C et al.. Thyroid as a target of adjuvant autoimmunity/inflammatory syndrome due to mRNA-based SARS-CoV2 vaccination: from Graves' disease to silent thyroiditis. J Endocrinol Invest. 2022;45(4):875–882. https://doi.org/10.1007/s40618-021-01707-0 Crossref, Medline, Google ScholarRotondi M, Coperchini F, Ricci G et al.. Detection of SARS-COV-2 receptor ACE-2 mRNA in thyroid cells: a clue for COVID-19-related subacute thyroiditis. J Endocrinol Invest. 2021;44(5):1085–1090. https://doi.org/10.1007/s40618-020-01436-w Crossref, Medline, Google Scholar FiguresReferencesRelatedDetails 2 February 2023Volume 84Issue 2ISSN (print): 1750-8460ISSN (online): 1759-7390 Metrics History Published online 14 February 2023 Published in print 2 February 2023 Information© MA Healthcare LimitedPDF download