Circulating tumor DNA as a Prognostic Factor in Patients with Resectable Hepatic Metastases of Uveal Melanoma.

Pascale Mariani,François-Clément Bidard,Aurore Rampanou,Alexandre Houy,Vincent Servois,Toulsie Ramtohul,Gaelle Pierron,Marion Chevrier,Benjamin Renouf,Olivier Lantz,Sophie Gardrat, Anne Vincent-Salomon, Sergio Sergio-Roman,Manuel Rodrigues,Sophie Piperno-Neumann,Nathalie Cassoux,Marc-Henri Stern,Shufang Renault

Annals of surgery（2023）

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摘要

This study is the first to report ctDNA detection rate and prognostic impact in UM patients eligible for surgical resection of their liver metastases. If confirmed by further studies in this setting, this non-invasive biomarker could inform treatment decisions in UM patients with liver metastases.

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关键词

circulating tumor DNA, ddPCR, liver metastases resection, prognostic value, uveal melanoma

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