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Mid-titer human convalescent plasma administration results in suboptimal prophylaxis against SARS-CoV-2 infection in rhesus macaques.

Brandon J Beddingfield,Nicholas J Maness,Skye Spencer,Jay Rappaport,Pyone Pyone Aye,Kasi Russell-Lodrigue,Lara A Doyle-Meyers,Robert V Blair,HongMei Gao,David Montefiori,Chad J Roy

Frontiers in immunology（2023）

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Abstract
Results indicate that prophylactic administration with mid-titer CP is not effective in reducing disease severity of SARS-CoV-2 infection in the rhesus COVID-19 disease model.
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Key words
COVID-19,SARS-CoV-2,convalescent plasma,prophylaxis,rhesus macaque
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