Clinical consequences of diagnostic variability in the histopathological evaluation of early rectal cancer.

Lisanne J H Smits,Annabel S van Lieshout, Robbert J I Bosker,Stijn Crobach,Eelco J R de Graaf,Mariska Hage,Miangela M Laclé,Freek C P Moll,Leon M G Moons,Koen C M J Peeters,Henderik L van Westreenen,Nicole C T van Grieken,Jurriaan B Tuynman

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology（2023）

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摘要

This study demonstrated that there is substantial interobserver variability between pathologists, especially in the assessment of lymphovascular invasion. Pathologists play a key role in treatment allocation after local excision of early rectal cancer, therefore interobserver variability needs to be reduced to decrease the number of patients that are over- or undertreated.

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Clinical consequences,Diagnostic variability,Early rectal cancer,Lymphovascular invasion

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