Sex-Specific Alterations of the Lung Transcriptome at Birth in Mouse Offspring Prenatally Exposed to Vanilla-Flavored E-Cigarette Aerosols and Enhanced Susceptibility to Asthma.

Alexandra Noël, Sultan Yilmaz,Tori Farrow, Matthew Schexnayder,Oliver Eickelberg,Tomislav Jelesijevic

International journal of environmental research and public health（2023）

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摘要

Overall, these data demonstrate that in utero e-cig aerosol exposure alters the developing mouse lung transcriptome at birth in a sex-specific manner and provide evidence that the inhalation of e-cig aerosols is detrimental to the respiratory health of offspring by increasing the offspring' susceptibility to developing lung diseases later in life.

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asthma,developmental origins of health and disease,electronic cigarette,electronic nicotine delivery system (ENDS),in utero exposures,prenatal exposures

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