PNPLA3 148M/M Is More Susceptible to Palmitic Acid-Induced Endoplasmic Reticulum Stress-Associated Apoptosis in HepG2 Cells.

Yunzhi Chen,Xuemei Yan, Tian Wang,Hongrong Deng,Xiaojie Deng,Fen Xu,Hua Liang

International journal of endocrinology（2023）

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摘要

PNPLA3 148M/M cells were more susceptible to PA-induced lipid deposition and ER stress-related apoptosis than 148I/I cells, and the proapoptotic susceptibility of PNPLA3 148M/M is independent of LPC.

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关键词

hepg2 cells,apoptosis,acid-induced,stress-associated

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