Microchimerism in multiple sclerosis: The association between sex of offspring and MRI features in women with multiple sclerosis.

Alessia Bianchi,Maria Aprile,Giuseppe Schirò,Claudia Gasparro,Salvatore Iacono, Michele Andolina,Maurizio Marrale,Irene Gattuso,Giuseppe La Tona,Massimo Midiri,Cesare Gagliardo,Giuseppe Salemi,Paolo Ragonese

Frontiers in neuroscience（2023）

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摘要

Our findings suggested an association between the sex of offspring and brain atrophy. Considering the sex of offspring as an indirect marker of fMCs, we speculated that fMCs could accumulate in different brain areas modulating MS neuropathological processes.

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关键词

magnetic resonance imaging,microchimerism,multiple sclerosis,pregnancy,regional volumes,sex of offspring,sexual chromosomes

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