Asbestos Fibers Enhance the TMEM16A Channel Activity in Xenopus Oocytes.

the TMEM16A channels endogenously expressed by oocytes are targets for asbestos fibers and represent a powerful tool for asbestos-membrane interaction studies. Interestingly, TMEM16A channels are highly expressed in many types of tumors, including some asbestos-related cancers, suggesting them, for the first time, as a possible early target of crocidolite-mediated tumorigenic effects on target cell membranes.