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Asbestos Fibers Enhance the TMEM16A Channel Activity in Xenopus Oocytes.

Annalisa Bernareggi,Martina Zangari,Andrew Constanti,Paola Zacchi,Violetta Borelli,Alessandro Mangogna,Paola Lorenzon,Giuliano Zabucchi

Membranes（2023）

Cited 2|Views15
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Abstract
the TMEM16A channels endogenously expressed by oocytes are targets for asbestos fibers and represent a powerful tool for asbestos-membrane interaction studies. Interestingly, TMEM16A channels are highly expressed in many types of tumors, including some asbestos-related cancers, suggesting them, for the first time, as a possible early target of crocidolite-mediated tumorigenic effects on target cell membranes.
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TMEM16A channels,Xenopus oocytes,asbestos fibers,crocidolite,voltage clamp
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