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Trefoil factor family proteins as potential diagnostic markers for mucinous invasive ovarian carcinoma.

Elisabeth Werner Rönnerman,Daniella Pettersson,Szilárd Nemes,Pernilla Dahm-Kähler,Anikó Kovács,Per Karlsson,Toshima Z Parris,Khalil Helou

Frontiers in oncology（2022）

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Abstract
Taken together, these findings suggest that the TFF proteins may play a pivotal role in tumor initiation and progression for the MC histotype. Moreover, these novel histotype-specific diagnostic biomarkers may not only improve patient stratification of early-stage ovarian carcinomas but may also be candidates for the development of molecular targeted therapies.
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Key words
biomarkers,histotype,molecular classification,mucinous ovarian carcinoma,trefoil factor gene family
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