CD146+ Umbilical Cord Mesenchymal Stem Cells Exhibit High Immunomodulatory Activity and Therapeutic Efficacy in Septic Mice.

Lin Zhang,Xiaoxu Zhang,Yubin Liu,Weiyuan Zhang,Chu-Tse Wu,Lisheng Wang

Journal of inflammation research（2023）

Cited 1|Views15

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Abstract

Compared with CD146-MSCs, CD146+MSCs can accelerate the end of the inflammatory response and have robust anti-inflammatory effects, by increasing the Treg cells, promoting macrophage phagocytosis, enhancing the reparative macrophage, secreting more VEGF, etc.

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Key words

UC-CD146±MSCs,anti-inflammatory,macrophages,sepsis

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