Effects of plasma-derived exosomes from the normal and thin Bactrian camels on hepatocellular carcinoma and their differences at transcriptome and proteomics levels.

Hongqiang Yao,Siriguleng Yu,Yuchen Luo, Ming Wang,Xiuying Wang,Siriguleng Xu, Yufei Chen, Zhifeng Xie

Frontiers in oncology（2023）

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摘要

Normal Bactrian camel plasma-derived exosomes may inhibit the growth of HCC cells through regulating pathways of Ras, Ras-Association Proximate 1 (Rap1), phosphoinositide 3-kinase-protein kinase B (PI3K-Akt), mitogen-activated protein kinase (MAPK), adenosine monophosphate-activated protein kinase (AMPK), and canonical Wnt signaling pathways.

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关键词

Bactrian camel,exosomes,hepatocellular carcinoma,proteomics,small sequencing

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