Combined analysis of PHOX2B at two time points and its value for further risk stratification in high-risk neuroblastoma.

Zhixia Yue,Chao Gao,Tianyu Xing,Wen Zhao,Chao Duan,Xisi Wang,Mei Jin,Yan Su

Pediatric blood & cancer（2023）

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摘要

MRD risk stratification based on PHOX2B levels at two time points (after two and six cycles of induction chemotherapy) provided a stratification system for high-risk NB, which successfully predicted treatment outcomes. Our results present an effective method for further stratification of high-risk NB.

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关键词

PHOX2B,high risk,minimal residual disease,neuroblastoma,risk stratification,survival

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