Thymosin α-1 in cancer therapy: Immunoregulation and potential applications

Yiting Wei,Yunpeng Zhang, Pengcheng Li,Chunguang Yan,Lixin Wang

International Immunopharmacology（2023）

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摘要

•Thymosin α-1 stimulates pleiotropic immune responses in different diseases.•Thymosin α-1 regulates immune cells depends on activation of toll-like receptors.•Thymosin α-1 has synergistic effect with chemotherapy by enhancing antitumor response.•Thymosin α-1 has therapeutic effect by combination with immune checkpoint inhibitors.

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关键词

Thymosin α-1 (Tα-1),Immune response,Toll-like receptors,Cancer therapy

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