Long non-coding RNA LGALS8-AS1 facilitates PLAGL2-mediated malignant phenotypes in gastric cancer.

Gang Wang,Kuan Shen,Jian Xiao,Hao Fan,Yuanhang Wang,Kanghui Liu,Xinyi Zhou,Quan Cheng,Yongchang Miao,Zekuan Xu,Li Yang

The journal of gene medicine（2023）

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摘要

In brief, we revealed the tumor promoting role of the LGALS8-AS1/miR-138-5p/PLAGL2 molecular signaling axis in GC, and our findings provide enlightenment for further understanding of the mechanism of tumorigenesis and development of GC, making LGALS8-AS1 a possible new diagnostic or therapeutic target for GC.

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关键词

LGALS8-AS1,PLAGL2,gastric cancer,malignant phenotype,miR-138-5p

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