Peripheral lymphocytes and lactate dehydrogenase correlate with response and survival in head and neck cancers treated with immune checkpoint inhibitors.

Cassie Pan,Qian Vicky Wu,Jenna Voutsinas,Jeffrey J Houlton,Brittany Barber,Zain H Rizvi,Emily Marchiano,Neal Futran,George E Laramore,Jay J Liao,Upendra Parvathaneni,Renato G Martins,Jonathan R Fromm,Cristina P Rodriguez

Cancer medicine（2023）

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摘要

In the largest study to date examining PBBMs in ICI-treated R/M HNSCCs, our variable selection method revealed PBBMs prognostic for survival and response to immunotherapy. These biomarkers warrant further investigation in a prospective study along with validation with CPS biomarker.

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关键词

biomarkers,check point control,head and neck cancer,medical oncology,prognostic factor

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