Clinical Features, Genetic Findings, and Risk Stratification in Arrhythmogenic Right Ventricular Cardiomyopathy: Data From a Brazilian Cohort.

Natália Quintella Sangiorgi Olivetti,Luciana Sacilotto,Fanny Wulkan,Gabrielle D'Arezzo Pessente,Mariana Lombardi Peres de Carvalho,Danilo Moleta,Denise Tessariol Hachul,Pedro Veronese,Carina Hardy,Cristiano Pisani,Tan Chen Wu,Marcelo Luiz Campos Vieira, Lucas Arraes de França, Matheus de Souza Freitas,Carlos Eduardo Rochitte, Sávia Christina Bueno,Vitor Bastos Lovisi,José Eduardo Krieger,Maurício Scanavacca,Alexandre da Costa Pereira,Francisco da Costa Darrieux

Circulation. Arrhythmia and electrophysiology（2023）

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摘要

Our study demonstrated the characteristics of a specific cohort with a high prevalence of arrhythmic burden at presentation, male predominance, younger age and HF severe outcomes. Our main results suggest that the presence and extension of low QRS voltage can be a risk predictor for HF-death/HTx in ARVC patients, regardless of the arrhythmic risk. This study can contribute to the global ARVC risk stratification, adding new insights to the international current scientific knowledge.

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关键词

arrhythmogenic right ventricular cardiomyopathy,genetics,heart failure,heart transplantation,risk assessment,sudden cardiac death

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