The relationship between radiation dose and bevacizumab-related imaging abnormality in patients with brain tumors: A voxel-wise normal tissue complication probability (NTCP) analysis.

Mia Salans,Jordan Houri,Roshan Karunamuni,Austin Hopper,Rachel Delfanti,Tyler M Seibert,Naeim Bahrami,Yasamin Sharifzadeh,Carrie McDonald,Anders Dale,Vitali Moiseenko,Nikdokht Farid, Jona A Hattangadi-Gluth

PloS one（2023）

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摘要

BRIA is likely a radiation dose-dependent phenomenon in patients with brain tumors receiving bevacizumab and radiotherapy. The combination of radiation effects and tumor microenvironmental factors in potentiating BRIA in this population should be further investigated.

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关键词

brain tumors,radiation dose,imaging abnormality,bevacizumab-related,voxel-wise

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