Oxymatrine ameliorates experimental autoimmune encephalomyelitis by rebalancing the homeostasis of gut microbiota and reducing blood-brain barrier disruption.

Frontiers in cellular and infection microbiology(2022)

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Abstract
OMAT may alleviate the clinical and pathological symptoms of MS by correcting dysbiosis, restoring gut ecological and functional microenvironment, and inhibiting immune cell-mediated inflammation to remodel the brain-gut axis.
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Key words
brain-gut axis,experimental autoimmune encephalomyelitis,gut microbiota,oxymatrine,short-chain fatty acids
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