Equisetum arvense Inhibits Alveolar Bone Destruction in a Rat Model with Lipopolysaccharide (LPS)-Induced Periodontitis.

Fumie Shiba,Hisako Furusho,Takashi Takata, Rika Shimizu,Mutsumi Miyauchi

International journal of dentistry（2022）

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摘要

These findings demonstrated that topical EA suppressed alveolar bone resorption in the rat model with . -LPS-induced periodontitis by maintaining a balance in RANKL/OPG ratio via the pathways of NF-B, Wnt/-catenin, and Sema3A/Neuropilin-1. Therefore, EA possesses the potential to prevent bone destruction through inhibiting osteoclastogenesis attributed to cytokine burst under plaque accumulation.

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关键词

lipopolysaccharide

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