Imperatorin derivative OW1, a new vasoactive compound, attenuates cell proliferation and migration by inhibiting Nox1-mediated oxidative stress.
The Journal of pharmacy and pharmacology(2023)
摘要
OW1 may inhibit vascular remodelling by downregulating the Nox1-ROS-MAPK/MMP signalling pathway.
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关键词
MAPKs,Nox1,ROS,imperatorin derivative OW1,vascular remodelling
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