A fluorescent probe for alkylating agents and its quantification of triflate as a genotoxic impurity.

Dan Zhang,Sifan Wang,Fangxi Yang,Qingrong Qi,Yanfang Li,Wencai Huang

Chemical communications (Cambridge, England)（2023）

引用 0|浏览17

暂无评分

摘要

The responses of a reaction-based fluorescent probe BI-Py towards alkyl halide, epoxide, carbonate, sulfate, sulphonate and triflate were evaluated and the probe achieved selective detection of ethyl triflate in acetonitrile with a LOD of 1.08 μM. BI-Py exhibited great potential for detecting triflate as a genotoxic impurity in drug substances.

查看译文

关键词

fluorescent probe,genotoxic impurity,triflate

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要