Effect of the Application of Exosome on Gastric Cancer.

Combinatorial chemistry & high throughput screening(2023)

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Abstract
Gastric cancer is one of the most common and highest mortality rate cancers in the world. Exosomes are vesicles secreted by cells carrying a large amount of information such as protein and RNA. Numerous studies have confirmed that exosomes are involved in various stages of the occurrence and development of gastric cancer and play an important role.With the gradual development, exosomes are widely developed in the diagnosis and treatment of gastric cancer. In this review, we made a basic overview of exosome, and discussed the role of exosome in the occurrence, proliferation, invasion, metastasis and drug resistance of gastric cancer. In addition, we emphasized the powerful effect and bright development prospect of exosome in the diagnosis and treatment of gastric cancer. The data of the discovery, diagnosis, treatment and prognosis of gastric cancer are not particularly optimistic, but the discovery of exosome, applied in diagnosis and treatment, provides a new and effective way to improve the survival rate of patients with gastric cancer.
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Key words
Exosome,diagnosis,gastric cancer,physiological function,prognosis,treatment
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