Three Cases of Lactic Acidosis Caused by Biguanides
CUREUS JOURNAL OF MEDICAL SCIENCE(2022)
Abstract
Biguanides may cause lactic acidosis (LA) in elderly patients. We report three cases of LA after the administration of biguanides. Case I was an 8.5-year-old man with no hepatic dysfunction who was discharged, case 2 was a 67-year-old man with no hepatic dysfunction who was discharged, and case 3 was a 77-year-old woman with hepatic dysfunction who died. Therefore, caution should be exercised in administering biguanides to elderly patients with hepatic dysfunction.
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Key words
biguanides,lactic acidosis,diabetes mellitus,case report,acute care medicine
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